Two sample MR report
Phosphatidylethanolamine (18:0_20:4) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 21 | 0.9972952 | 0.4233627 | 0.0293866 |
| Weighted median | 21 | 0.5165035 | 0.2776682 | 0.0628648 |
| Inverse variance weighted | 21 | 0.4920300 | 0.1948569 | 0.0115671 |
| Simple mode | 21 | 0.9346377 | 0.4330115 | 0.0432242 |
| Weighted mode | 21 | 0.5814094 | 0.2898678 | 0.0585981 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 20.11409 | 19 | 0.3877427 |
| Inverse variance weighted | 22.00790 | 20 | 0.3400820 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1221012 | 0.0912902 | 0.1968493 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0051848 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
