Two sample MR report
Phosphatidylethanolamine (O-18:1_18:2) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 29 | -0.2647464 | 0.5775894 | 0.6503588 |
| Weighted median | 29 | -0.2381532 | 0.3607631 | 0.5091656 |
| Inverse variance weighted | 29 | -0.4916531 | 0.2486265 | 0.0479878 |
| Simple mode | 29 | 0.2871498 | 0.7797845 | 0.7154619 |
| Weighted mode | 29 | 0.2871498 | 0.5927973 | 0.6318711 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 29.37260 | 27 | 0.3430674 |
| Inverse variance weighted | 29.58008 | 28 | 0.3835661 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0329149 | 0.0753685 | 0.665788 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006198 | 0 | TRUE | 0.0468892 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
