Two sample MR report
Phosphatidylinositol (18:0_20:3) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 34 | -0.9402654 | 0.3724256 | 0.0167345 |
| Weighted median | 34 | -0.6301880 | 0.2691358 | 0.0192052 |
| Inverse variance weighted | 34 | -0.6199067 | 0.1812994 | 0.0006280 |
| Simple mode | 34 | -0.6836669 | 0.4898957 | 0.1721747 |
| Weighted mode | 34 | -0.6245038 | 0.2713221 | 0.0278021 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 32.17994 | 32 | 0.4578439 |
| Inverse variance weighted | 33.15542 | 33 | 0.4596775 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0546059 | 0.0554433 | 0.3320635 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0042775 | 0 | TRUE | 2e-07 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
