Two sample MR report
Triacylglycerol (53:3) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 25 | -0.1002471 | 0.6133834 | 0.8716051 |
| Weighted median | 25 | -0.2376606 | 0.3792869 | 0.5309224 |
| Inverse variance weighted | 25 | -0.6358276 | 0.2452684 | 0.0095316 |
| Simple mode | 25 | -1.2981564 | 0.6892493 | 0.0718151 |
| Weighted mode | 25 | -0.1788361 | 0.4607059 | 0.7013058 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 20.01951 | 23 | 0.6407343 |
| Inverse variance weighted | 20.92702 | 24 | 0.6430268 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0730564 | 0.0766892 | 0.3506824 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007823 | 0 | TRUE | 0.023048 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
