Two sample MR report
Triacylglycerol (54:3) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 30 | -0.1088157 | 0.6216472 | 0.8623046 |
| Weighted median | 30 | -0.5007073 | 0.3680908 | 0.1737407 |
| Inverse variance weighted | 30 | -0.5568525 | 0.2467171 | 0.0240050 |
| Simple mode | 30 | -1.4430595 | 0.7588052 | 0.0671796 |
| Weighted mode | 30 | -0.3976752 | 0.5161057 | 0.4472175 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 32.00710 | 28 | 0.2742221 |
| Inverse variance weighted | 32.71366 | 29 | 0.2894381 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0602778 | 0.0766703 | 0.438357 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0008281 | 0 | TRUE | 0.0190507 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
