Two sample MR report
Triacylglycerol (56:3) levels against finn-b-I9_PVT_EXNONE
Date: 16 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 24 | -1.2497434 | 0.6020819 | 0.0498151 |
| Weighted median | 24 | -0.3578519 | 0.3432139 | 0.2971105 |
| Inverse variance weighted | 24 | -0.5914193 | 0.2427324 | 0.0148299 |
| Simple mode | 24 | 0.4289846 | 0.7315026 | 0.5632899 |
| Weighted mode | 24 | -0.0695049 | 0.5805557 | 0.9057436 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 22.47447 | 22 | 0.4318923 |
| Inverse variance weighted | 23.92776 | 23 | 0.4078179 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1079201 | 0.0904817 | 0.2456815 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007347 | 0 | TRUE | 0.0394238 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
