Two sample MR report
Crohn disease || id:finn-b-K11_CROHN against AtopicDermatitis
Date: 26 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.025 | 0.061 | 0.707 |
| Weighted median | 5 | 0.024 | 0.021 | 0.244 |
| Inverse variance weighted | 5 | 0.019 | 0.026 | 0.448 |
| Simple mode | 5 | 0.023 | 0.030 | 0.472 |
| Weighted mode | 5 | 0.023 | 0.024 | 0.393 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.68 | 3 | 0.022 |
| Inverse variance weighted | 11.84 | 4 | 0.019 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.015 | 0.018 | 0.473 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.713 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
