Two sample MR report


Inflammatory bowel disease || id:finn-b-K11_IBD against AtopicDermatitis

Date: 26 January, 2026


Results from two sample MR:

method nsnp b se pval
MR Egger 13 -0.070 0.152 0.652
Weighted median 13 -0.012 0.024 0.602
Inverse variance weighted 13 0.012 0.063 0.850
Simple mode 13 -0.032 0.035 0.375
Weighted mode 13 0.009 0.034 0.788

Heterogeneity tests

method Q Q_df Q_pval
MR Egger 204 11 0
Inverse variance weighted 210 12 0

Test for directional horizontal pleiotropy

egger_intercept se pval
0.015 0.024 0.562

Test that the exposure is upstream of the outcome

snp_r2.exposure snp_r2.outcome correct_causal_direction steiger_pval
0 0 TRUE 0.55

Note - R^2 values are approximate


Forest plot of single SNP MR

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Comparison of results using different MR methods

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Funnel plot

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Leave-one-out sensitivity analysis

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