Two sample MR report
Irritable bowel syndrome || id:finn-b-K11_IBS against AtopicDermatitis
Date: 26 January, 2026
Results from two sample MR:
| method |
nsnp |
b |
se |
pval |
| MR Egger |
11 |
0.033 |
0.047 |
0.507 |
| Weighted median |
11 |
-0.002 |
0.028 |
0.932 |
| Inverse variance weighted |
11 |
0.007 |
0.020 |
0.713 |
| Simple mode |
11 |
-0.004 |
0.048 |
0.927 |
| Weighted mode |
11 |
-0.005 |
0.043 |
0.909 |
Heterogeneity tests
| method |
Q |
Q_df |
Q_pval |
| MR Egger |
8.65 |
9 |
0.470 |
| Inverse variance weighted |
9.00 |
10 |
0.532 |
Test for directional horizontal pleiotropy
| egger_intercept |
se |
pval |
| -0.004 |
0.007 |
0.57 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure |
snp_r2.outcome |
correct_causal_direction |
steiger_pval |
| 0 |
0 |
TRUE |
0.822 |
Note - R^2 values are approximate
Forest plot of single SNP MR

Comparison of results using different MR methods

Funnel plot

Leave-one-out sensitivity analysis
