Two sample MR report
Ulcerative colitis || id:finn-b-K11_ULCER against AtopicDermatitis
Date: 26 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.005 | 0.106 | 0.966 |
| Weighted median | 7 | -0.060 | 0.026 | 0.019 |
| Inverse variance weighted | 7 | -0.066 | 0.040 | 0.102 |
| Simple mode | 7 | -0.060 | 0.032 | 0.114 |
| Weighted mode | 7 | -0.060 | 0.039 | 0.172 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 31.1 | 5 | 0 |
| Inverse variance weighted | 33.5 | 6 | 0 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.012 | 0.02 | 0.558 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.63 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
