Two sample MR report
ENSG00000089685 || id:eqtl-a-ENSG00000089685 against Liver cell carcinoma || id:ieu-b-4953
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.000 | 0.000 | 0.910 |
| Weighted median | 3 | 0.000 | 0.000 | 0.122 |
| Inverse variance weighted | 3 | 0.000 | 0.000 | 0.107 |
| Simple mode | 3 | -0.001 | 0.001 | 0.183 |
| Weighted mode | 3 | 0.000 | 0.000 | 0.364 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.129 | 1 | 0.719 |
| Inverse variance weighted | 1.809 | 2 | 0.405 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0 | 0.418 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.023 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
