Two sample MR report
ENSG00000121966 || id:eqtl-a-ENSG00000121966 against Liver cell carcinoma || id:ieu-b-4953
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.003 | 0.003 | 0.410 |
| Weighted median | 5 | 0.000 | 0.000 | 0.872 |
| Inverse variance weighted | 5 | 0.000 | 0.000 | 0.639 |
| Simple mode | 5 | 0.000 | 0.001 | 0.926 |
| Weighted mode | 5 | 0.000 | 0.000 | 0.898 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.69 | 3 | 0.639 |
| Inverse variance weighted | 2.52 | 4 | 0.642 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0 | 0.431 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.701 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
