Two sample MR report
ENSG00000145675 || id:eqtl-a-ENSG00000145675 against Liver cell carcinoma || id:ieu-b-4953
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.000 | 0.001 | 0.850 |
| Weighted median | 6 | 0.000 | 0.000 | 0.486 |
| Inverse variance weighted | 6 | 0.000 | 0.000 | 0.769 |
| Simple mode | 6 | 0.001 | 0.000 | 0.269 |
| Weighted mode | 6 | 0.000 | 0.000 | 0.397 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.75 | 4 | 0.045 |
| Inverse variance weighted | 9.77 | 5 | 0.082 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0 | 0.943 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.179 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
