Two sample MR report
ENSG00000174775 || id:eqtl-a-ENSG00000174775 against Liver cell carcinoma || id:ieu-b-4953
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.002 | 0.002 | 0.442 |
| Weighted median | 3 | 0.000 | 0.000 | 0.745 |
| Inverse variance weighted | 3 | 0.000 | 0.001 | 0.844 |
| Simple mode | 3 | 0.001 | 0.001 | 0.425 |
| Weighted mode | 3 | -0.001 | 0.001 | 0.352 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.45 | 1 | 0.118 |
| Inverse variance weighted | 7.07 | 2 | 0.029 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0 | 0.401 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.645 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
