Two sample MR report
Axin-1 levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | -0.1196025 | 0.2766805 | 0.6738925 |
| Weighted median | 13 | 0.0689125 | 0.1148181 | 0.5483804 |
| Inverse variance weighted | 13 | 0.2038181 | 0.0834557 | 0.0145968 |
| Simple mode | 13 | 0.0907582 | 0.2205259 | 0.6879223 |
| Weighted mode | 13 | 0.0477634 | 0.1141659 | 0.6830677 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.195861 | 11 | 0.6038190 |
| Inverse variance weighted | 10.699023 | 12 | 0.5548733 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0290473 | 0.0236921 | 0.245785 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.6e-05 | 0 | TRUE | 0.4750217 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
