Two sample MR report
C-C motif chemokine 19 levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 37 | 0.1352147 | 0.0551758 | 0.0194012 |
| Weighted median | 37 | 0.1335513 | 0.0439003 | 0.0023490 |
| Inverse variance weighted | 37 | 0.0749419 | 0.0380845 | 0.0490937 |
| Simple mode | 37 | 0.1305356 | 0.1245372 | 0.3015486 |
| Weighted mode | 37 | 0.1159099 | 0.0432350 | 0.0110079 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 39.39801 | 35 | 0.2795699 |
| Inverse variance weighted | 41.88961 | 36 | 0.2305164 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.010828 | 0.007278 | 0.1457662 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000656 | 0 | TRUE | 0.0031784 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
