Two sample MR report
Fibroblast growth factor 5 levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 34 | -0.0002049 | 0.0385351 | 0.9957903 |
| Weighted median | 34 | -0.0525569 | 0.0325500 | 0.1063865 |
| Inverse variance weighted | 34 | -0.0612957 | 0.0304453 | 0.0440823 |
| Simple mode | 34 | -0.1931951 | 0.1099562 | 0.0881905 |
| Weighted mode | 34 | -0.0546339 | 0.0308420 | 0.0857283 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 33.29128 | 32 | 0.4042087 |
| Inverse variance weighted | 39.08051 | 33 | 0.2153877 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.016265 | 0.006895 | 0.0245968 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0169485 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
