Two sample MR report
Interleukin-17A levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 24 | -0.0963863 | 0.1995623 | 0.6338755 |
| Weighted median | 24 | -0.2103676 | 0.1031345 | 0.0413762 |
| Inverse variance weighted | 24 | -0.1909429 | 0.0712632 | 0.0073753 |
| Simple mode | 24 | 0.2798132 | 0.1487375 | 0.0726559 |
| Weighted mode | 24 | -0.2516178 | 0.1069174 | 0.0275236 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 19.57979 | 22 | 0.6093063 |
| Inverse variance weighted | 19.83711 | 23 | 0.6517170 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0091695 | 0.0180762 | 0.617016 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 8.41e-05 | 0 | TRUE | 0.3428802 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
