Two sample MR report
Interleukin-1-alpha levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 25 | 0.1825401 | 0.0744405 | 0.0222104 |
| Weighted median | 25 | 0.1303738 | 0.0578368 | 0.0241857 |
| Inverse variance weighted | 25 | 0.0856665 | 0.0404912 | 0.0343719 |
| Simple mode | 25 | 0.0675107 | 0.0864908 | 0.4426963 |
| Weighted mode | 25 | 0.1101374 | 0.0524879 | 0.0465811 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 15.65306 | 23 | 0.8697136 |
| Inverse variance weighted | 18.05820 | 24 | 0.8001761 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0159306 | 0.0102722 | 0.1345896 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000247 | 0 | TRUE | 0.1066099 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
