Two sample MR report
Interleukin-6 levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | 0.0670585 | 0.1032434 | 0.5293325 |
| Weighted median | 13 | 0.1307462 | 0.0731973 | 0.0740646 |
| Inverse variance weighted | 13 | 0.1282484 | 0.0594183 | 0.0308968 |
| Simple mode | 13 | 0.1112935 | 0.1011137 | 0.2926268 |
| Weighted mode | 13 | 0.1112935 | 0.0685948 | 0.1306624 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 8.808764 | 11 | 0.6395391 |
| Inverse variance weighted | 9.333995 | 12 | 0.6741690 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0091192 | 0.012583 | 0.4837497 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000206 | 0 | TRUE | 0.0971913 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
