Two sample MR report
Leukemia inhibitory factor receptor levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 30 | -0.3019551 | 0.0778823 | 0.0005837 |
| Weighted median | 30 | -0.2198291 | 0.0633896 | 0.0005245 |
| Inverse variance weighted | 30 | -0.1204267 | 0.0418013 | 0.0039650 |
| Simple mode | 30 | -0.0497996 | 0.1312869 | 0.7072148 |
| Weighted mode | 30 | -0.2241420 | 0.0564636 | 0.0004344 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 21.88391 | 28 | 0.7866372 |
| Inverse variance weighted | 29.46626 | 29 | 0.4409900 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0235466 | 0.0085512 | 0.0102339 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009734 | 0 | TRUE | 0.001107 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
