Two sample MR report
Neurturin levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 25 | 0.0059771 | 0.2321523 | 0.9796818 |
| Weighted median | 25 | -0.3646466 | 0.1205781 | 0.0024933 |
| Inverse variance weighted | 25 | -0.2651777 | 0.0859775 | 0.0020405 |
| Simple mode | 25 | -0.3739489 | 0.1831152 | 0.0522726 |
| Weighted mode | 25 | -0.3919627 | 0.1222659 | 0.0037869 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 24.01173 | 23 | 0.4031590 |
| Inverse variance weighted | 25.65626 | 24 | 0.3708338 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.023012 | 0.018335 | 0.2220519 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 8.25e-05 | 0 | TRUE | 0.3607043 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
