Two sample MR report
Tumor necrosis factor receptor superfamily member 9 levels against gastric_cancer
Date: 02 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 39 | 0.0457055 | 0.1395036 | 0.7450385 |
| Weighted median | 39 | -0.0701541 | 0.0666372 | 0.2924431 |
| Inverse variance weighted | 39 | -0.1537667 | 0.0501266 | 0.0021581 |
| Simple mode | 39 | -0.1679610 | 0.1086674 | 0.1304794 |
| Weighted mode | 39 | -0.1148239 | 0.0681198 | 0.1000657 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 44.06556 | 37 | 0.1974796 |
| Inverse variance weighted | 46.84750 | 38 | 0.1537397 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0219492 | 0.0143613 | 0.1349286 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002146 | 0 | TRUE | 0.1359871 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
